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CDL & medical · Updated Oct 2026

What disqualifies you from a DOT physical? Blood pressure, sleep apnea, medications, vision and diabetes

Few conditions automatically fail a DOT physical. Under 49 CFR 391.41, the certified medical examiner decides whether a condition is likely to affect safe driving.[1] Source: 49 CFR 391.41: Physical qualifications for drivers (eCFR) (opens in a new tab) Many conditions lead to a shorter card rather than a fail.[8] Source: Appendix A to Part 391: Medical Advisory Criteria (opens in a new tab) The regulation bars use of any Schedule I drug.[1] Source: 49 CFR 391.41: Physical qualifications for drivers (eCFR) (opens in a new tab) Since April 28, 2026, DEA has listed marijuana in an FDA-approved product or under a state medical marijuana license in Schedule III, but all other marijuana is still Schedule I.[12] Source: DEA: Rescheduling of FDA-Approved Products Containing Marijuana From Schedule I to Schedule III, 91 FR 22714 (Federal Register) (opens in a new tab) FMCSA's 2024 examiner handbook says a driver who uses marijuana can't be qualified, even where state law allows it.[10] Source: FMCSA: Medical Examiner's Handbook, 2024 Edition (PDF) (opens in a new tab) FMCSA's advisory criteria also say a driver with blood pressure of 180/110 or higher shouldn't be certified until it's brought down.[8] Source: Appendix A to Part 391: Medical Advisory Criteria (opens in a new tab) Losing a hand, arm, foot or leg disqualifies you unless you get an FMCSA Skill Performance Evaluation certificate.[1] Source: 49 CFR 391.41: Physical qualifications for drivers (eCFR) (opens in a new tab) Most other conditions have a path back: treatment, a special standard, or an FMCSA exemption.

How certificate length works

Blood pressure limits and card length

FMCSA's Medical Advisory Criteria (Appendix A to Part 391, Jan. 2024) and its hypertension FAQ give examiners these ranges. They're guidance, not law, and the examiner confirms an elevated reading with at least two more measurements.[8] Source: Appendix A to Part 391: Medical Advisory Criteria (opens in a new tab)[11] Source: Federal Register: Qualifications of Drivers; Medical Examiner's Handbook Regulatory Guidance (2024-01056) (opens in a new tab)

Reading (systolic/diastolic)FMCSA stageWhat the guidance says about your card
Under 140/90NormalMay be certified for up to 2 years. If you're being treated for hypertension, at least yearly.
140–159 / 90–99Stage 11-year card. If you're still above 140/90 but under 160/100 at the next exam, a one-time 3-month card to get it to 140/90 or less.
160–179 / 100–109Stage 2One-time 3-month card to start or adjust medication. If you get to 140/90 or less, a 1-year card.
180/110 or higherStage 3Not qualified, even for a short time, until you're at 140/90 or less and tolerating treatment. Then 6-month cards, rechecked every 6 months.

Sources: Appendix A to Part 391, section E[8] Source: Appendix A to Part 391: Medical Advisory Criteria (opens in a new tab), and FMCSA hypertension FAQ[9] Source: FMCSA: What is the effect on driver certification based on FMCSA hypertension stages? (opens in a new tab).

Sleep apnea

Medications (including ADHD meds, opioids and marijuana)

Diabetes (insulin-treated and not)

Vision and hearing

Seizures and other conditions with exemptions

If you're not qualified: options

FAQs

What blood pressure disqualifies you from a DOT physical?

A reading of 180/110 or higher (Stage 3) means you can't be certified, even briefly, until it's at 140/90 or less and treatment is working. Then cards run 6 months at a time. Stage 1 (140–159/90–99) gets a 1-year card, and Stage 2 (160–179/100–109) a one-time 3-month card.[8] Source: Appendix A to Part 391: Medical Advisory Criteria (opens in a new tab)

Can you pass a DOT physical with sleep apnea?

Often, yes. FMCSA's regulations set no sleep apnea screening requirement, waiting period, maximum card length, required test or treatment, or compliance standard. The examiner decides under the respiratory standard. FMCSA's 2024 handbook says treated moderate-to-severe sleep apnea doesn't stop you from being certified, and whether treatment is working is the examiner's call.[10] Source: FMCSA: Medical Examiner's Handbook, 2024 Edition (PDF) (opens in a new tab)

What medications disqualify you from a DOT physical?

Any Schedule I drug disqualifies you.[1] Source: 49 CFR 391.41: Physical qualifications for drivers (eCFR) (opens in a new tab) Since April 28, 2026, marijuana in an FDA-approved product or under a state medical license is Schedule III, but other marijuana is still Schedule I.[12] Source: DEA: Rescheduling of FDA-Approved Products Containing Marijuana From Schedule I to Schedule III, 91 FR 22714 (Federal Register) (opens in a new tab) That doesn't make a medical card a pass: FMCSA's 2024 examiner handbook says marijuana users can't be qualified.[10] Source: FMCSA: Medical Examiner's Handbook, 2024 Edition (PDF) (opens in a new tab) DOT also still tests for marijuana.[13] Source: DOT ODAPC: Part 40 Q&A on §§ 40.137, 40.141, 40.151 (marijuana) (opens in a new tab) Other controlled drugs, like ADHD stimulants or opioids, can be OK if the prescriber knows your history and says it won't affect safe driving. The examiner can use FMCSA's optional 391.41 CMV Driver Medication Form.[8] Source: Appendix A to Part 391: Medical Advisory Criteria (opens in a new tab)

Can you drive a truck with insulin-treated diabetes?

Yes. Since 2018, 49 CFR 391.46 lets you be certified if your treating clinician completes the ITDM Assessment Form (MCSA-5870) and you see the examiner within 45 days. The card lasts up to 12 months. You need 3 months of electronic glucose-meter records for the full year. Otherwise it's capped at 3 months.[4] Source: 49 CFR 391.46: Insulin-treated diabetes mellitus (opens in a new tab)

Can you fail a DOT physical and try again?

Yes. The examiner reports a "not qualified" result to FMCSA, and any card you had stops being valid. You need a new exam before you can be certified again, for example once the problem is treated or you qualify under a special standard or exemption.[2] Source: 49 CFR 391.43: Medical examination; certificate of physical examination (opens in a new tab)

Sources

  1. 49 CFR 391.41: Physical qualifications for drivers (eCFR)  (opens in a new tab). Current text, eCFR up to date as of 2026-10-21.
  2. 49 CFR 391.43: Medical examination; certificate of physical examination  (opens in a new tab). Current text as of 2026-10-21.
  3. 49 CFR 391.45: Persons who must be medically examined and certified  (opens in a new tab). Last amended 91 FR 45661, July 21, 2026.
  4. 49 CFR 391.46: Insulin-treated diabetes mellitus  (opens in a new tab). Rule 83 FR 47520, Sept. 19, 2018, amended 2019.
  5. 49 CFR 391.44: Alternative vision standard  (opens in a new tab). Rule 87 FR 3417, Jan. 21, 2022.
  6. 49 CFR 391.47: Resolution of conflicts of medical evaluation  (opens in a new tab). Last amended Nov. 17, 2023.
  7. 49 CFR 391.49: Alternative standards for loss or impairment of limbs (SPE)  (opens in a new tab). Current text as of 2026-10-21.
  8. Appendix A to Part 391: Medical Advisory Criteria  (opens in a new tab). 89 FR 3579, Jan. 19, 2024. Advisory guidance, not binding.
  9. FMCSA: What is the effect on driver certification based on FMCSA hypertension stages?  (opens in a new tab). Last updated Apr. 1, 2014.
  10. FMCSA: Medical Examiner's Handbook, 2024 Edition (PDF)  (opens in a new tab). January 2024, section 4.8.3.6 (OSA).
  11. Federal Register: Qualifications of Drivers; Medical Examiner's Handbook Regulatory Guidance (2024-01056)  (opens in a new tab). Published Jan. 22, 2024.
  12. DEA: Rescheduling of FDA-Approved Products Containing Marijuana From Schedule I to Schedule III, 91 FR 22714 (Federal Register)  (opens in a new tab). Published and effective Apr. 28, 2026. Adds 21 CFR 1308.13(g); a D.C. Circuit stay was denied Sept. 9, 2026, and court review is pending.
  13. DOT ODAPC: Part 40 Q&A on §§ 40.137, 40.141, 40.151 (marijuana)  (opens in a new tab). Posted May 2026.